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Translational Research

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Translational Research

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Research Frontiers in Patient-Derived Xenograft Models

Creation of personalized tumor models from patient tissue implanted in mice to predict treatment response and resistance mechanisms.

Stromal-Tumour Coevolution in Humanized PDX Systems
PDX-Derived Organoids and Organ-on-Chip Integration
Pharmacokinetic Heterogeneity Across Patient-Derived Models
Clonal Dynamics and Treatment-Induced Selection Pressure
Microbiome Engraftment and Immune Checkpoint Modulation
Spatial Transcriptomics of Patient Tumour Architecture
PDX-Based Biomarker Discovery for Precision Oncology
Immunological Memory in Serial PDX Transplantation
Metabolic Adaptation in Xenograft-Host Interfaces
Multi-Omic Prediction of Clinical Drug Response Trajectories

All Translational Research PhD categories