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Sleep Medicine

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Research Frontiers in Orexin Deficiency and Narcolepsy Type One Pathophysiology

Characterizing hypocretin system degeneration in narcolepsy-cataplexy and developing targeted therapies for orexin neuron replacement.

Orexin Neuron Loss and Autoimmune Cascades in Narcolepsy
Hypocretin Signaling Collapse Across Brain Sleep-Wake Networks
Microglial Activation in Orexinergic System Degeneration
Sleep Fragmentation Dynamics Without Orexin Control
Cataplexy Mechanisms Beyond Monoaminergic Compensation
Orexin Receptor Sensitization as Therapeutic Vulnerability
Circadian Desynchrony in Hypocretin-Deficient Brains
Glutamatergic Remodeling at Orexin Synapse Loss
Narcolepsy Type One and Entropy in Neural Sleep Architecture
Orexin Peptide Restoration Across the Blood-Brain Barrier

All Sleep Medicine PhD categories