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Optogenetics

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Optogenetics

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Research Frontiers in Microbial Opsin Engineering and Protein Design

Development of novel microbial opsins with improved kinetics, spectral properties, and expression levels through directed evolution and rational design approaches.

Non-Canonical Chromophore Integration in Microbial Opsins
Spectral Multiplexing Through Rational Opsin Architecture
Ultrafast Kinetics Engineering for High-Frequency Neural Control
Membrane Topology Redesign in Archaeal Light Sensors
Calcium-Independent Voltage Sensing in Engineered Opsins
Cross-Kingdom Opsin Trafficking and Biogenesis
Red-Shifted Variants Beyond Natural Evolutionary Constraints
Cooperative Light-Gating in Engineered Opsin Oligomers
Photocycle Modulation Through Loop Insertion Engineering
Chimeric Opsin Scaffolds for Synthetic Signaling Pathways

All Optogenetics PhD categories