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Molecular Cancer Research

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Molecular Cancer Research

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Research Frontiers in CRISPR Base Editing for Oncogenic Driver Mutations

Develops precision base editing strategies to directly correct cancer-causing point mutations without generating double-strand breaks in tumor cells.

ABE-Mediated Reversion of RAS Family Oncogenic Hotspots
Prime Editing Precision in TP53 Restoration Pathways
Epigenetic Silencing as Escape Mechanism in Base-Edited Tumors
Off-Target Base Editing and Clonal Selection Pressure
Delivery Barriers in CRISPR Base Editing of Solid Tumors
Synthetic Lethal Vulnerabilities Exposed by Oncogenic Reversion
Base Editor Fidelity in Polyploid Cancer Cells
Chromatin Context Dependency of CRISPR-Induced Mutations
Immunogenicity of Base-Edited Cancer Cell Populations
Mosaic Editing Landscapes and Tumor Heterogeneity Dynamics

All Molecular Cancer Research PhD categories