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Medical Biology

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Medical Biology

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Research Frontiers in Protein Misfolding and Neurodegenerative Disease

Examination of amyloid-beta and tau aggregation mechanisms in Alzheimer''s disease and development of anti-aggregation therapeutics.

Prion-Like Propagation in Non-Prion Neurodegenerative Diseases
Proteostatic Collapse at the Blood-Brain Barrier Interface
Chaperone-Resistant Protein Aggregates and Neuroinflammation
Phase Separation and Pathological Condensate Formation in Neurodegeneration
Misfolded Protein Clearance in Aged Glial Cells
Conformational Spreading of Tau and α-Synuclein Variants
Intrinsically Disordered Proteins and Disease Susceptibility Networks
Lipid Membranes as Nucleation Sites for Aggregation Cascades
Post-Translational Modification Driving Protein Misfolding Pathways
Oligomeric Intermediates as Drivers of Synaptic Dysfunction

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