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Comparative Genomics

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Comparative Genomics

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Research Frontiers in Ortholog and Paralog Inference Methods

Develops computational algorithms to distinguish between orthologs and paralogs for accurate functional annotation across genomes.

Synteny-Guided Ortholog Discovery Across Divergent Clades
Paralog Subfunctionalization and Neofunctionalization Trajectories
Machine Learning Inference of Orthologs in Fragmentary Genomes
Reconciling Gene Trees with Species Trees Under Whole-Genome Duplications
Cross-Domain Ortholog Assignment in Microbial Pan-Genomes
Horizontal Gene Transfer Detection Through Ortholog Incongruence Patterns
Codon Usage Bias as a Signature of Ortholog Evolution
Ortholog Clustering in the Absence of Reference Assemblies
Functional Constraint and Sequence Divergence in Paralog Pairs
Rapid Ortholog Inference in Metagenomic and Environmental Datasets

All Comparative Genomics PhD categories