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Research Frontiers in Transformer Models for Protein Immunogenicity Prediction

Large language models trained to predict immunogenic epitopes in mRNA-encoded proteins for cancer and infectious disease applications.

Epitope Geometry and Transformer Attention Mechanisms
Codon Optimization Through Learned Immunogenicity Landscapes
MHC Allotype Polymorphism in Sequence-to-Immunity Models
Contextual Immunogenicity: mRNA Secondary Structure Effects
Transformer-Driven Prediction of Cryptic Neoantigen Emergence
Cross-Species Immunogenicity Transfer Learning Boundaries
Temporal Dynamics of T-Cell Activation in Transformer Embeddings
Adjuvant Modulation of Predicted Immunogenicity Responses
Rare Variant Immunogenicity in Underrepresented Populations
Transformer Uncertainty Quantification in Immunotoxicity Prediction

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